中文名稱：GFAP抗體
英文名稱：GFAP antibody，Affinity purified Rabbit polyclonal GFAP antibody，Polyclonal GFAP antibody, Anti-GFAP antibody, Glial Fibrillary Acid Protein antibody, Glial marker, Glial Filament Protein antibody
貨號：70R-GR031
品牌：Fitzgerald
SpecificityHuman
Cross ReactivityMouse, rat
ApplicationsFC, IHC, WB
ImmunogenGFAP antibody was raised in rabbit using the C terminus of the 50 kDa human protein as the immunogen.
HostRabbit
Concentration1.0 mg/ml
Form & BufferAffinity purified and supplied in PBS, with 0.02% NaN3.
Method of PurificationGFAP antibody was purified by affinity chromatography.
IsotypeIgG
Usage RecommendationsFC: 1:200-1:500, IHC: 1:100-1:200, WB: 1:500-1:1,000
StorageStore at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard InformationThis product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Biological SignificanceGFAP is one of the major intermediate filament proteins of mature astrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development.
Product UsePurified polyclonal GFAP antibody specific for Human GFAP for use in Flow Cytometry, Immunohistochemistry and Western Blot.
Post-Translational ModificationsGFAP is Phosphorylated by PKN1.
Sequence InformationGFAP is composed of 432 amino acids with a molecular weight of 49880 Da. GFAP is a member of the intermediate filament family.
Implications in DiseaseMutations in GFAP expression cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alexander disease, also known as fibrinoid leukodystrophy, is a slowly progressing and fatal neurodegenerative disease. It is a very rare di
Database LinksEntrez Gene: 2670 Human, Omim: 137780 Human, SwissProt: P14136 Human, Unigene: 514227 Human
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